Projects

The interdisciplinary research project at the interface between engineering and life sciences foresees the process development and validation for printing three-dimensional vascularized bone replacement tissue by combining innovative bioprinting technologies. One of the main objectives in the development of the printing process is the production of vascularized tissue with functional vessels according to specific designs. The second main objective relates to the study of the processes involved in the formation of blood vessels, depending on the composition and spatial arrangement of the various biomaterials such as bone and endothelial cells with hydrogels, and growth factors. The viability and operability of the artificial bone tissue will be validated by in vitro and in vivo experiments. These findings may contribute to a clinical use of bioprinting technologies for therapeutic purposes and will significantly strengthen the of research in the field of bioengineering of vascularized tissue.