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Universal Platform for Nucleic-Acid Based in vitro Diagnostics

Projektbild

Project description

Goal of the project UniSond is to establish a novel analysis technique that combinses sensitive DNA-detection by polymerase chain reaction (PCR) with a cost-effective universal microarray. The DNA-analysis technique is automated by integration into a microfluidic LabDisk. Generic DNA-probes are immobilized onto the microarray is which are independent of the DNA-tagets to be detected. The generic detection array format enables reduced fabrication costs of the disposable LabDisk. UniSond comprises the complete diagnostic process chain of nucleic-acid based sample analyses. Sample transfer to central laboratories is thus circumvented and the analysis can be directly performed at the point of care as exemplarily the doctor´s office at the bedside in hospitals. The UniSond system will be validated on the basis of respiratory pathogen detections. For more technological information, please see link below.

Start/End of project

01.08.2011 until 31.07.2014

Project manager

Dr. Michael Lehnert (Prof. Dr. Roland Zengerle)

Contact person

Dr. Michael Lehnert
Phone:+49 761 203-73229

Partners

Altona Diagnostics GmbH/Hamburg, Askion GmbH/Gera, Fraunhofergesellschaft München (F.-Institut für Physikalische Messtechnik/Freiburg), Jenoptik Polymer Systems GmbH/Triptis, Medizinisches Versorgungszentrum Dr. Stein + Kollegen/Mönchengladbach, Progen Biotechnik GmbH/Heidelberg

Funding

BMBF FKZ 16SV5405

Keywords

Lab-on-a-Chip Biosensoren, bio sensors, analytics, diagnostics, funktionelle Oberflächen, Analytik & Diagnostik, Lab-on-a-Chip
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