Projects
Universal Platform for Nucleic-Acid Based in vitro Diagnostics
Project description
Goal of the project UniSond is to establish a novel analysis technique that combinses sensitive DNA-detection by polymerase chain reaction (PCR) with a cost-effective universal microarray.
The DNA-analysis technique is automated by integration into a microfluidic LabDisk.
Generic DNA-probes are immobilized onto the microarray is which are independent of the DNA-tagets to be detected. The generic detection array format enables reduced fabrication costs of the disposable LabDisk.
UniSond comprises the complete diagnostic process chain of nucleic-acid based sample analyses. Sample transfer to central laboratories is thus circumvented and the analysis can be directly performed at the point of care as exemplarily the doctor´s office at the bedside in hospitals.
The UniSond system will be validated on the basis of respiratory pathogen detections. For more technological information, please see link below.
Start/End of project
01.08.2011 until 31.07.2014
Project manager
Dr. Michael Lehnert (Prof. Dr. Roland Zengerle)
Contact person
Dr. Michael Lehnert
Phone:+49 761 203-73229
Partners
Altona Diagnostics GmbH/Hamburg,
Askion GmbH/Gera,
Fraunhofergesellschaft München (F.-Institut für Physikalische Messtechnik/Freiburg),
Jenoptik Polymer Systems GmbH/Triptis,
Medizinisches Versorgungszentrum Dr. Stein + Kollegen/Mönchengladbach, Progen Biotechnik GmbH/Heidelberg
Funding
BMBF FKZ 16SV5405
Keywords
Lab-on-a-Chip
Biosensoren, bio sensors, analytics, diagnostics, funktionelle Oberflächen, Analytik & Diagnostik, Lab-on-a-Chip