Projects

The objective of 3D-Bio-Net is to explore an open and generic platform for ‘3D-Bio-Printing’, for the digital printing of artificial tissue and their exemplary testing in two important fields of application (tissue engineering and organ-on-chip). The complete workflow for the digital production of three-dimensional artificial biological tissues will be tested and demonstrated with a laboratory device designed specifically for the purpose of 3D-Bio-Printing, a CAD and control software, a range of validated biomaterials and a collection of process descriptions. Accordingly, a 3D-Bio-Printer is being developed, which will feature disposable components for sterile processing of biomaterials, the use of three different printing processes in combination and a close relationship to software and data structures from the field of industrial 3D-Printing. The 3D-Bio-Printer enables the fully automatic printing of complex three-dimensional structures consisting of living tissue or organ models using materials and processes that are successively developed and optimized as part of the 3D-Bio-Printing platform. With the help of the 3D-Bio-Printer, printing processes and bioinks are developed, tested and validated in order to create a library of materials and process descriptions that will facilitate 3D-Bio-Printing in the future and enable standardization. Two applications from the areas of replacement tissue research (bone or cartilage) and in vitro organ models (blood-brain-barrier or kidney) will be addressed with the 3D-Bio-Printer and a microfluidic chip to test the 3D-Bio-Printing platform. 12/2020, report of BMBF: https://www.bmbf.de/de/3d-biodrucker-loesen-tierversuche-ab-13326.html