Projects

In this project we will develop a novel light sheet microscope, which is equipped with two spatial light modulators (SLM) for high end 4D imaging of large scattering specimen and precise Opto genetic switching. Unprecedented image quality will be achieved by using holographically shaped, object adapted, confocal Bessel beams for imaging various samples provided by the collaboration partners. By a novel postprocessing method, we are able to separate diffusive and ballistic photons, which leads to high image quality also deep inside the specimen. By developing a feedback controlled, holographic multipoint laser illumination through the second SLM, we will realize dynamic and precise Opto genetic switching in large specimen with superior precision and efficiency. Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany´s Excellence Strategy – EXC-2189 – Project ID: 390939984